Source: J Pharm Sci  1982 Jul;71(7):739-41

Title: Cardiac stimulant action of constituents of Aloe saponaria.

Authors: Yagi A, Shibata S, Nishioka I, Iwadare S, Ishida Y.

Abstract: A highly potent cardiotonic substance, calcium isocitrate, was isolated from Aloe saponaria, using solvent partition, nonionic porous resin, and gel permation chromatographies.  Cardiac stimulant activity of synthesized stereoisimers of calcium isocitrate was demonstrated in isolated guinea pig atria. PMID: 7120054 [PubMed - indexed for MEDLINE]